Don Rowe was a career minor leaguer when the Mets drafted him from the Pittsburgh Pirates in the 1962 Rule 5 draft. The left-handed pitcher made his Major League debut on opening day in 1963 pitching 2 2/3 innings of scoreless relief. He would go on to pitch in 26 games, 25 out of the bullpen, for the Mets before being sent down to the minors at the end of July. At the time, he was 0-0 with 4.28 ERA in 54 2/3 innings. In his one start against the Philadelphia Phillies, he allowed 3 runs in 4 2/3 innings.
Rowe would not pitch for Mets again spending the next 2 ½ seasons pitching for the Buffalo Bisons, the Mets top minor league club. During that time, he won 10 and lost 14 games.
While with the Mets Rowe wore number 29.